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Background and aims: Hyperuricaemia can lead to gout and is associated with an increased risk of cardiometabolic disease. We aimed to investigate the prevalence of hyperuricaemia and its related factors in Chinese children and adolescents.
Methods: We pooled data from 11 population-based studies comprising 54, participants aged years. The sex- and age-standardized prevalence of hyperuricaemia was estimated overall and by sex, age, weight status, geographic region and survey year. Results: Serum uric acid SUA increased gradually from 3 to 11 years with no significant sex difference, and then increased dramatically during years. The estimated overall prevalence of hyperuricaemia was The prevalence increased with growing age 3.
The prevalence was higher in North than in South In multivariable regression analyses, sex, age, obesity, region and survey year were independently associated with odds of hyperuricaemia. Conclusions: The prevalence of hyperuricaemia in Chinese children and adolescents is unexpectedly high. The findings suggest an urgent need to implement effective interventions to reduce risk of hyperuricaemia in Chinese youths.
Meaning: Our findings indicate that hyperuricaemia is an important health problem in Chinese children and adolescents, and effective intervention strategies are needed to reduce its burden. Keywords: Children; adolescents; hyperuricaemia; prevalence; uric acid.
Abstract Background and aims: Hyperuricaemia can lead to gout and is associated with an increased risk of cardiometabolic disease. Substances Uric Acid. Grants and funding.