Increased expression of translocator protein TSPO marks pro-inflammatory microglia but does not predict neurodegeneration. Mol Imaging Biol. Sci Rep. Molecules ; Eur J Med Chem. J Neuroinflammation. From structure-activity relationships on thiazole derivatives to the in vivo evaluation of a new radiotracer for cannabinoid subtype 2 PET imaging.
Mol Pharm. J Med Chem. Discovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X7 receptor antagonists. Determination and reduction of translocator protein TSPO ligand rs discrimination. J Cereb Blood Flow Metab ; 37 2 : Stepwise reversible nanomechanical buckling in a viral capsid.
Derivatives of the pyrazolo[1,5-a]pyrimidine acetamide DPA as translocator protein TSPO ligands and pro-apoptotic agents in human glioblastoma. Eur J Pharm Sci. Pharmacological evaluation of novel bioisosteres of an adamantanyl benzamide P2X7 receptor antagonist. ACS Chem Neurosci. Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks.
Pharmacological evaluation of a novel series of urea, thiourea and guanidine derivatives as P2X7 receptor antagonists. Bioorg Med Chem Lett. Imaging of neuroinflammation in Alzheimer's disease, multiple sclerosis and stroke: Recent developments in positron emission tomography.
Biochim Biophys Acta. J Nucl Med. Chem Soc Rev. Structureβactivity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues. Forensic Toxicol. Appl Radiat Isot. Efficient tritiation of the translocator protein 18 kDa selective ligand DPA J Labelled Comp Radiopharm. Farde L. Clin Transl Imaging. Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [11C]A as a novel tracer of neuroinflammation. Neurobiol Aging. PET radioligands for in vivo visualization of neuroinflammation.
